Sickle Cell Anemia Makio Murayama Hand Signed TLS Dated 1976

  

"Sickle Cell Anemia" Makio Murayama Hand Signed TLS Dated 1976. Biochemist best known for his work on. Was sent to live with relatives at age age four upon the death of his father. He was raised in Japan for the next ten years, returning to San Francisco when. After graduating from Lowell High School in 1933, he went on.

To the University of California where he graduated with bachelor's (1938) and. Master's (1940) degrees in biochemistry and physics.

With the outbreak of World. War II and the subsequent mass forced removal of Japanese Americans from the. West Coast, he was called to Chicago to work as a physicist on what would. Become the Manhattan Project, while his family was sent to an American. But he was turned away because of his Japanese ancestry.

Eventually found a position as a blood chemist at the Children's Hospital of. Michigan and took similar positions at the Department of Pediatrics at the.

University of Michigan and the Children's Pediatric Service at Bellevue. Hospital in New York over the next five years. He went on to finish his Ph. He subsequently did postdoctoral work at the. California Institute of Technology working the Linus Pauling (1954-56) and at. The University of Pennsylvania (1956-58). In October of 1958, he joined the. Staff of the National Institutes of Health in Bethesda, Maryland, where he. Would work for the rest of his career. He engaged in landmark research on.

Sickle cell anemia, which had engaged his interest in Michigan where had worked. With child patients stricken with the disease.

He famously built a three-foot. Tall model of the hemoglobin molecule over a six-year period in his home.

Basement, using some 70,000 screws to represent atoms, which helped him gain a. Clearer understanding of the disease and led to groundbreaking research on the. Disease and a new treatment for it. He gained acclaim and fame for his work.

Receiving the 1969 Association for Sickle Cell Anemia award and the 1972 Martin. He continued to work at NIH into. He died in Michigan on January 8, 2012.